منابع مشابه
Cytokines in Autoimmune Disease
Cellular Therapy Laboratory, CancerCare Manitoba, Winnipeg, MB, Canada Institute of Pharmacology, Taishan Medical University, Taian, China The Institute of Clinical Research and Translational Medicine, Gansu Provincial Hospital, Lanzhou, China Department of Physiology, University of Toronto, Toronto, ON, Canada Department of Endocrinology & Metabolism, Qilu Hospital of Shandong University, Jina...
متن کاملCytokines in autoimmune lacrimal gland disease in MRL/MpJ mice.
PURPOSE MRL/MpJ-+/+ (MRL/+) and MRL/MpJ-lpr/lpr (MRL/lpr) mice show spontaneous development of a T-cell-driven lacrimal gland inflammation that is a model for Sjögren syndrome. The lacrimal gland lesions in these mice were evaluated by quantitative RT-PCR for selected cytokine mRNA for the relative contributions of T-helper (Th)1 versus Th2 immune responses and by RT-PCR and immunohistochemistr...
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I n this issue, Saoudi and colleagues expand on their previous observation that development of experimental allergic encephalitis (EAE) can be suppressed by preimmunizing rats with a myelin basic protein (MBP)-derived peptide that has been coupled to an anti-IgD antibody (1, 2). Their observations illustrate how antigen presentation by a particular cell type can induce a form of tolerance, immu...
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Recent developments in medicine have given us a better insight into a group of disorders known as autoimmune diseases. In particular, advances have occurred in our understanding of the Autoimmune Inner Ear Disease (AIED). In this article, the authors review the different postulated theories in the pathogenesis of this disease. The clinical presentation, the available para-clinical diagnostic to...
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T lymphocytes that are involved in cellular mediated immunity include two types known as TCD8+ (Cytotoxic T lymphocytes) and TCD4+ (helper T lymphocytes). TCD4+ has four main subtypes, including TH1, TH2, TH17, and Treg Lymphocytes.TH17 lymphocytes play a role in defense against microbes that TH1 and TH2 lymphocytes have not the ability to respond to them. The most important cytokines, which ar...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2017
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2017/5089815